Polynucleotides are suitable for all skin types and age groups and it will optimise the outcomes of further aesthetic treatments. The applications range from the face, scalp, eyebrow and neck to décolletage and hands, giving more radiant and rejuvenated skin. It also can be used to revive the delicate area around the eyes and promotes hair growth for the scalp and eyebrow. Polynucleotides can also be used to treat more mature, damaged skin and for the remodelling of stretch marks and depressed scars.